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Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes

Identifying the early gene program induced by GnRH would help understand how GnRH-activated signaling pathways modulate gonadotrope secretory response. We previously analyzed GnRH-induced early genes in LβT2 cells, however these lack GnRH self-potentiation, a physiological attribute of gonadotropes....

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Autors principals: Yuen, Tony, Choi, Soon Gang, Pincas, Hanna, Waring, Dennis W., Sealfon, Stuart C., Turgeon, Judith L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919063/
https://ncbi.nlm.nih.gov/pubmed/22127306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.11.017
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