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What happens when replication and transcription complexes collide?

The arrest of replication forks due to collisions with transcription complexes leads to genomic instability and cell death. Mechanisms that promote the progression of replication forks past transcription complexes are therefore essential for propagation and preservation of the genome. Recent studies...

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Autores principales: Pomerantz, Richard T., O’Donnell, Mike
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918965/
https://ncbi.nlm.nih.gov/pubmed/20581460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.13.12122
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