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A Unified Theory of Sepsis-Induced Acute Kidney Injury: Inflammation, microcirculatory dysfunction, bioenergetics and the tubular cell adaptation to injury

Given that the leading clinical conditions associated with Acute kidney injury (AKI), namely, sepsis, major surgery, heart failure and hypovolemia, are all associated with shock, it is tempting to attribute all AKI to ischemia on the basis of macro-hemodynamic changes. However, an increasing body of...

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Detalhes bibliográficos
Main Authors: Gomez, Hernando, Ince, Can, De Backer, Daniel, Pickkers, Peter, Payen, Didier, Hotchkiss, John, Kellum, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918942/
https://ncbi.nlm.nih.gov/pubmed/24346647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000052
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