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A Unified Theory of Sepsis-Induced Acute Kidney Injury: Inflammation, microcirculatory dysfunction, bioenergetics and the tubular cell adaptation to injury

Given that the leading clinical conditions associated with Acute kidney injury (AKI), namely, sepsis, major surgery, heart failure and hypovolemia, are all associated with shock, it is tempting to attribute all AKI to ischemia on the basis of macro-hemodynamic changes. However, an increasing body of...

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Bibliografiske detaljer
Main Authors: Gomez, Hernando, Ince, Can, De Backer, Daniel, Pickkers, Peter, Payen, Didier, Hotchkiss, John, Kellum, John A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918942/
https://ncbi.nlm.nih.gov/pubmed/24346647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000052
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