Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity

The four dengue virus (DENV) serotypes, DENV-1, -2, -3, and -4, are endemic throughout tropical and subtropical regions of the world, with an estimated 390 million acute infections annually. Infection confers long-term protective immunity against the infecting serotype, but secondary infection with...

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Auteurs principaux: Messer, William B., de Alwis, Ruklanthi, Yount, Boyd L., Royal, Scott R., Huynh, Jeremy P., Smith, Scott A., Crowe, James E., Doranz, Benjamin J., Kahle, Kristen M., Pfaff, Jennifer M., White, Laura J., Sariol, Carlos A., de Silva, Aravinda M., Baric, Ralph S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918811/
https://ncbi.nlm.nih.gov/pubmed/24385585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317350111
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