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Comparison of the isomerization mechanisms of human melanopsin and invertebrate and vertebrate rhodopsins
Comparative modeling and ab initio multiconfigurational quantum chemistry are combined to investigate the reactivity of the human nonvisual photoreceptor melanopsin. It is found that both the thermal and photochemical isomerization of the melanopsin 11-cis retinal chromophore occur via a space-savin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918805/ https://ncbi.nlm.nih.gov/pubmed/24449866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309508111 |
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