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Mutational landscape of yeast mutator strains

The acquisition of mutations is relevant to every aspect of genetics, including cancer and evolution of species on Darwinian selection. Genome variations arise from rare stochastic imperfections of cellular metabolism and deficiencies in maintenance genes. Here, we established the genome-wide spectr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Serero, Alexandre, Jubin, Claire, Loeillet, Sophie, Legoix-Né, Patricia, Nicolas, Alain G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918763/
https://ncbi.nlm.nih.gov/pubmed/24449905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314423111
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