Diversity at the variable-joining region boundary of lambda light chains has a pronounced effect on immunoglobulin ligand-binding activity.

By recombining lambda light (L) chains having known variable (V) region amino acid or nucleotide sequences with a heavy (H) chain from a myeloma protein or a monoclonal antibody, we obtained reconstituted Igs that differed from each other in sequence by only one or a few amino acid substitutions at...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Azuma, T, Igras, V, Reilly, E B, Eisen, H N
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1984
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6435124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.19.6139
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!