Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice

AIMS/HYPOTHESIS: Adult beta cells have a diminished ability to proliferate. Phosphatase and tensin homologue (PTEN) is a lipid phosphatase that antagonises the function of the mitogenic phosphatidylinositol 3-kinase (PI3K) pathway. The objective of this study was to understand the role of PTEN and P...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Yang, Kai-Ting, Bayan, Jennifer-Ann, Zeng, Ni, Aggarwal, Richa, He, Lina, Peng, Zhechu, Kassa, Anketse, Kim, Melissa, Luo, Zhiou, Shi, Zhenrong, Medina, Vivian, Boddupally, Keerthi, Stiles, Bangyan L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918745/
https://ncbi.nlm.nih.gov/pubmed/24162585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3085-8
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares