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Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice
AIMS/HYPOTHESIS: Adult beta cells have a diminished ability to proliferate. Phosphatase and tensin homologue (PTEN) is a lipid phosphatase that antagonises the function of the mitogenic phosphatidylinositol 3-kinase (PI3K) pathway. The objective of this study was to understand the role of PTEN and P...
Tallennettuna:
Päätekijät: | , , , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2013
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918745/ https://ncbi.nlm.nih.gov/pubmed/24162585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3085-8 |
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