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Gentamicin concentration gradients in scala tympani perilymph following systemic applications

In prior studies it was shown that round window membrane (RWM) application of gentamicin produced a robust baso-apical concentration gradient in the perilymph of scala tympani (ST) with peak concentrations in the basal turn of ST. These gradients potentially contribute to the clinical efficacy and s...

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Bibliographic Details
Main Authors: Hahn, Hartmut, Salt, Alec N., Schumacher, Ulrike, Plontke, Stefan K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918439/
https://ncbi.nlm.nih.gov/pubmed/24192668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355283
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