Synthesis of a gene for human growth hormone and its expression in Escherichia coli.

A gene coding for human growth hormone, which consists of 192 amino acids, was chemically synthesized. The synthesis entailed ligating 78 deoxyribooligonucleotides, which had been synthesized on polymer supports by the phosphotriester method with frequently occurring amino acid codons of Escherichia...

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Hlavní autoři: Ikehara, M, Ohtsuka, E, Tokunaga, T, Taniyama, Y, Iwai, S, Kitano, K, Miyamoto, S, Ohgi, T, Sakuragawa, Y, Fujiyama, K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC391837/
https://ncbi.nlm.nih.gov/pubmed/6091124
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