Use of short DNA oligonucleotides for determination of DNA sequence modifications induced by benzo[a]pyrene diol epoxide.

Various organic agents that alkylate DNA are known to induce mutations in bacterial and animal cells. The precise nature and location of modified DNA sequences in such mutants are often difficult to ascertain. In this report, a 10-base-pair oligomer (BamHI linker) is treated with (+/-)-trans-benzo[a...

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Main Authors: Wei, S J, Desai, S M, Harvey, R G, Weiss, S B
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC391833/
https://ncbi.nlm.nih.gov/pubmed/6091121
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