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The somatostatin analogue octreotide inhibits angiogenesis in the earliest, but not in advanced, stages of portal hypertension in rats

Background: Angiogenesis is an important determinant of the pathophysiology of portal hypertension contributing to the formation of portosystemic collateral vessels and the hyperdynamic splanchnic circulation associated to this syndrome. Somatostatin and its analogues, like octreotide, have been sho...

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Autori principali: Mejias, Marc, Garcia-Pras, Ester, Tiani, Carolina, Bosch, Jaime, Fernandez, Mercedes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918085/
https://ncbi.nlm.nih.gov/pubmed/18194463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00218.x
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