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Long-acting delivery systems for peptides: inhibition of rat prostate tumors by controlled release of [D-Trp6]luteinizing hormone-releasing hormone from injectable microcapsules.

Intramuscular injection of [6-D-tryptophan]-luteinizing hormone-releasing hormone [( D-Trp6]LH-RH) in microcapsules of poly(DL-lactide-co-glycolide), designed to release a controlled dose of the peptide over a 30-day period, decreased the weights of androgen-dependent Dunning prostate tumors in rats...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Redding, T W, Schally, A V, Tice, T R, Meyers, W E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1984
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6237365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.18.5845
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