Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis

Type 2 diabetes mellitus (DM) appears to be a significant risk factor for Alzheimer disease (AD). Insulin and insulin-like growth factor-1 (IGF-1) also have intense effects in the central nervous system (CNS), regulating key processes such as neuronal survival and longevity, as well as learning and...

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Main Authors: Bosco, Domenico, Fava, Antonietta, Plastino, Massimiliano, Montalcini, Tiziana, Pujia, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918038/
https://ncbi.nlm.nih.gov/pubmed/21435176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01318.x
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