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Comparison of normalization methods for differential gene expression analysis in RNA-Seq experiments: A matter of relative size of studied transcriptomes

In recent years, RNA-Seq technologies became a powerful tool for transcriptome studies. However, computational methods dedicated to the analysis of high-throughput sequencing data are yet to be standardized. In particular, it is known that the choice of a normalization procedure leads to a great var...

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Autors principals: Maza, Elie, Frasse, Pierre, Senin, Pavel, Bouzayen, Mondher, Zouine, Mohamed
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918003/
https://ncbi.nlm.nih.gov/pubmed/26442135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.25849
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