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No Major Role for Insulin-Degrading Enzyme in Antigen Presentation by MHC Molecules
Antigen presentation by MHC class I molecules requires degradation of epitope source proteins in the cytosol. Although the preeminent role of the proteasome is clearly established, evidence suggesting a significant role for proteasome-independent generation of class I ligands has been reported repea...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917890/ https://ncbi.nlm.nih.gov/pubmed/24516642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088365 |
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