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New Findings in Cleavage Sites Variability across Groups, Subtypes and Recombinants of Human Immunodeficiency Virus Type 1

BACKGROUND: Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS: In thi...

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Bibliografiske detaljer
Main Authors: Torrecilla, Esther, Llácer Delicado, Teresa, Holguín, África
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917854/
https://ncbi.nlm.nih.gov/pubmed/24516589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088099
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