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New Findings in Cleavage Sites Variability across Groups, Subtypes and Recombinants of Human Immunodeficiency Virus Type 1

BACKGROUND: Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS: In thi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Torrecilla, Esther, Llácer Delicado, Teresa, Holguín, África
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917854/
https://ncbi.nlm.nih.gov/pubmed/24516589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088099
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