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New Findings in Cleavage Sites Variability across Groups, Subtypes and Recombinants of Human Immunodeficiency Virus Type 1

BACKGROUND: Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS: In thi...

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Detalhes bibliográficos
Main Authors: Torrecilla, Esther, Llácer Delicado, Teresa, Holguín, África
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917854/
https://ncbi.nlm.nih.gov/pubmed/24516589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088099
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