Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC

Conjugated vaccines consisting of flagellin and antigen activate TLR5 and induce strong innate and adaptive immune responses. Objective of the present study was to gain further insight into the mechanisms by which flagellin fusion proteins mediate their immune modulating effects. In a mouse model of...

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Main Authors: Schülke, Stefan, Wolfheimer, Sonja, Gadermaier, Gabriele, Wangorsch, Andrea, Siebeneicher, Susanne, Briza, Peter, Spreitzer, Ingo, Schiller, Dirk, Loeschner, Bettina, Uematsu, Satoshi, Ryffel, Bernard, Akira, Shizuo, Waibler, Zoe, Vieths, Stefan, Toda, Masako, Scheurer, Stephan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917841/
https://ncbi.nlm.nih.gov/pubmed/24516564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087822
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