Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC

Conjugated vaccines consisting of flagellin and antigen activate TLR5 and induce strong innate and adaptive immune responses. Objective of the present study was to gain further insight into the mechanisms by which flagellin fusion proteins mediate their immune modulating effects. In a mouse model of...

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Main Authors: Schülke, Stefan, Wolfheimer, Sonja, Gadermaier, Gabriele, Wangorsch, Andrea, Siebeneicher, Susanne, Briza, Peter, Spreitzer, Ingo, Schiller, Dirk, Loeschner, Bettina, Uematsu, Satoshi, Ryffel, Bernard, Akira, Shizuo, Waibler, Zoe, Vieths, Stefan, Toda, Masako, Scheurer, Stephan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917841/
https://ncbi.nlm.nih.gov/pubmed/24516564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087822
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