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High glucose-induced resistance to 5-fluorouracil in pancreatic cancer cells alleviated by 2-deoxy-D-glucose

Abnormal glucose metabolism from hyperglycemia or diabetes aggravates the progression of pancreatic cancer. It is unknown whether high glucose has an impact on the antitumor effect of 5-fluorouracil (5-Fu) and whether targeting aberrant glucose metabolism using 2-deoxy-D-glucose (2-DG) may reverse t...

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Detalhes bibliográficos
Main Authors: CHENG, YAO, DIAO, DONGMEI, ZHANG, HAO, GUO, QI, WU, XUANDI, SONG, YONGCHUN, DANG, CHENGXUE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917746/
https://ncbi.nlm.nih.gov/pubmed/24649094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2013.211
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