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Hedgehog signaling inhibitor cyclopamine induces apoptosis by decreasing Gli2 and Bcl2 expression in human salivary pleomorphic adenoma cells

Pleomorphic adenoma is the most common benign neoplasm of the salivary gland. Few studies are currently available on pleomorphic adenoma cell apoptosis. The aim of this study was to investigate the effect of cyclopamine induction apoptosis in human salivary pleomorphic adenoma (HSPA) cells and the i...

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Détails bibliographiques
Auteurs principaux: SONG, MENG, OU, XUEPING, XIAO, CUICUI, XIAO, ZHONGMING, WEI, FANG, HONG, YAN
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917731/
https://ncbi.nlm.nih.gov/pubmed/24648943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2013.61
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