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Genomic insights into WNT/β-catenin signaling
The canonical WNT pathway regulates the stability of the proto-oncogene β-catenin and is aberrantly activated in many cancer types. Studies in a wide range of experimental models confirm that β-catenin activity is required for tumor initiation in cancers where this pathway is deregulated. However, t...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917662/ https://ncbi.nlm.nih.gov/pubmed/24365576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2013.11.007 |
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