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Targeting ion transport in cancer

The metabolism of cancer cells differs substantially from normal cells, including ion transport. Although this phenomenon has been long recognized, ion transporters have not been viewed as suitable therapeutic targets. However, the acidic pH values present in tumours which are well outside of normal...

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Detalhes bibliográficos
Main Authors: Oosterwijk, E., Gillies, R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917361/
https://ncbi.nlm.nih.gov/pubmed/24493755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0107
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