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A non-catalytic histidine residue influences the function of the metalloprotease of Listeria monocytogenes

Mpl, a thermolysin-like metalloprotease, and PC-PLC, a phospholipase C, are synthesized as proenzymes by the intracellular bacterial pathogen Listeria monocytogenes. During intracellular growth, L. monocytogenes is temporarily confined in a membrane-bound vacuole whose acidification leads to Mpl aut...

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Autori principali: Forster, Brian M., Bitar, Alan Pavinski, Marquis, Hélène
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for General Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917227/
https://ncbi.nlm.nih.gov/pubmed/24140648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.071779-0
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