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Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity

RecG is a helicase that is conserved in nearly all bacterial species. The prototypical Escherichia coli RecG promotes regression of stalled replication forks, participates in DNA recombination and DNA repair, and prevents aberrant replication. Mycobacterium tuberculosis RecG (RecG(Mtb)) is a DNA-dep...

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Detalhes bibliográficos
Main Authors: Zegeye, Ephrem Debebe, Balasingham, Seetha V., Laerdahl, Jon K., Homberset, Håvard, Kristiansen, Per E., Tønjum, Tone
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917224/
https://ncbi.nlm.nih.gov/pubmed/24169816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.072140-0
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