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Specific hepatitis B virus integration in hepatocellular carcinoma DNA through a viral 11-base-pair direct repeat.

Integrated hepatitis B virus (HBV) DNA sequences have been cloned from cellular DNA of two human liver tumors. The structure of the clones was determined by restriction mapping, and the host-viral DNA junctions were sequenced. In each clone one junction mapped to within an 11-base-pair sequence, 5&#...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dejean, A, Sonigo, P, Wain-Hobson, S, Tiollais, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391701/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6089197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.17.5350
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