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Inclusion of the orientational entropic effect and low-resolution experimental information for protein-protein docking in CAPRI

Inclusion of entropy is important and challenging for protein-protein binding prediction. Here, we present a statistical mechanics-based approach to empirically consider the effect of orientational entropy. Specifically, we globally sample the possible binding orientations based on a simple shape-co...

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Autori principali: Huang, Sheng-You, Yan, Chengfei, Grinter, Sam Z., Chang, Shan, Jiang, Lin, Zou, Xiaoqin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916956/
https://ncbi.nlm.nih.gov/pubmed/24227686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24435
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