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Stable transfer and expression of exogenous human globin genes in human erythroleukemia (K562) cells.

To study the expression of globin genes in human cells, human epsilon-globin genes were transferred into a K562 cell line, Bos, which synthesizes very low amounts of epsilon-globin mRNA. A plasmid (pSV2neo-epsilon) containing a complete epsilon-globin gene and 2 kilobases (kb) of 5' flanking DNA as...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Young, K, Donovan-Peluso, M, Bloom, K, Allan, M, Paul, J, Bank, A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6089193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.17.5315
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