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HSPCs Get their Motors Running for Asymmetric Fate Choice
Contractile forces are implicated in cell polarity and asymmetric division, but their contribution to cell fate is unclear. In this issue, Shin et al. show that myosin-II isoforms sense matrix stiffness in hematopoietic stem and progenitor cells, with polarized myosin-IIB promoting asymmetric self-r...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916825/ https://ncbi.nlm.nih.gov/pubmed/24388168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.12.002 |
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