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Human RPE Stem Cells Grown into Polarized RPE Monolayers on a Polyester Matrix Are Maintained after Grafting into Rabbit Subretinal Space

Transplantation of the retinal pigment epithelium (RPE) is being developed as a cell-replacement therapy for age-related macular degeneration. Human embryonic stem cell (hESC) and induced pluripotent stem cell (iPSC)-derived RPE are currently translating toward clinic. We introduce the adult human R...

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Autors principals: Stanzel, Boris V., Liu, Zengping, Somboonthanakij, Sudawadee, Wongsawad, Warapat, Brinken, Ralf, Eter, Nicole, Corneo, Barbara, Holz, Frank G., Temple, Sally, Stern, Jeffrey H., Blenkinsop, Timothy A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916756/
https://ncbi.nlm.nih.gov/pubmed/24511471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.11.005
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