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Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas.

Monoclonal antibodies (MAbs) of predefined specificity have been generated by utilizing a synthetic peptide reflecting amino acid positions 10-17 of the Hu-rasT24 gene product as immunogen. These MAbs, designated RAP-1 through RAP-5 (RA, ras; P, peptide), have been shown to react with the ras gene p...

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Autors principals: Hand, P H, Thor, A, Wunderlich, D, Muraro, R, Caruso, A, Schlom, J
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC391671/
https://ncbi.nlm.nih.gov/pubmed/6382261
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