Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain

FE65 is a cytosolic adapter protein and an important binding partner of amyloid precursor protein. Dependent on Thr668 phosphorylation in amyloid precursor protein, which influences amyloidogenic amyloid precursor protein processing, FE65 undergoes nuclear translocation, thereby transmitting a signa...

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Autors principals: Nensa, Fabian M., Neumann, Martin H. D., Schrötter, Andreas, Przyborski, Andre, Mastalski, Thomas, Susdalzew, Sergej, Looβe, Christina, Helling, Stefan, El Magraoui, Fouzi, Erdmann, Ralf, Meyer, Helmut E., Uszkoreit, Julian, Eisenacher, Martin, Suh, Jaehong, Guénette, Suzanne Y., Röhner, Nelli, Kögel, Donat, Theiss, Carsten, Marcus, Katrin, Müller, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916648/
https://ncbi.nlm.nih.gov/pubmed/24284412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.029280
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