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Matching Cross-linked Peptide Spectra: Only as Good as the Worse Identification

Chemical cross-linking mass spectrometry identifies interacting surfaces within a protein assembly through labeling with bifunctional reagents and identifying the covalently modified peptides. These yield distance constraints that provide a powerful means to model the three-dimensional structure of...

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Bibliografiske detaljer
Main Authors: Trnka, Michael J., Baker, Peter R., Robinson, Philip J. J., Burlingame, A. L., Chalkley, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916644/
https://ncbi.nlm.nih.gov/pubmed/24335475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.034009
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