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QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIα

Due to the high mortality rate in India, the identification of novel molecules is important in the development of novel and potent anticancer drugs. Xanthones are natural constituents of plants in the families Bonnetiaceae and Clusiaceae, and comprise oxygenated heterocycles with a variety of biolog...

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Detalhes bibliográficos
Main Authors: Alam, Sarfaraz, Khan, Feroz
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916431/
https://ncbi.nlm.nih.gov/pubmed/24516330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S51577
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