Foxp3(+) Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice

Accumulating evidence suggests that IL-9-mediated immunity plays a fundamental role in control of intestinal nematode infection. Here we report a different impact of Foxp3(+) regulatory T cells (Treg) in nematode-induced evasion of IL-9-mediated immunity in BALB/c and C57BL/6 mice. Infection with St...

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Autores principales: Blankenhaus, Birte, Reitz, Martina, Brenz, Yannick, Eschbach, Marie-Luise, Hartmann, Wiebke, Haben, Irma, Sparwasser, Tim, Huehn, Jochen, Kühl, Anja, Feyerabend, Thorsten B., Rodewald, Hans-Reimer, Breloer, Minka
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916398/
https://ncbi.nlm.nih.gov/pubmed/24516385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003913
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