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An alternate pathophysiologic paradigm of sepsis and septic shock: Implications for optimizing antimicrobial therapy
The advent of modern antimicrobial therapy following the discovery of penicillin during the 1940s yielded remarkable improvements in case fatality rate of serious infections including septic shock. Since then, pathogens have continuously evolved under selective antimicrobial pressure resulting in a...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916387/ https://ncbi.nlm.nih.gov/pubmed/24184742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/viru.26913 |
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