Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix

A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental conditions encountered by M. tuberculosis in the granu...

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Detalhes bibliográficos
Main Authors: Bacon, Joanna, Alderwick, Luke J., Allnutt, Jon A., Gabasova, Evelina, Watson, Robert, Hatch, Kim A., Clark, Simon O., Jeeves, Rose E., Marriott, Alice, Rayner, Emma, Tolley, Howard, Pearson, Geoff, Hall, Graham, Besra, Gurdyal S., Wernisch, Lorenz, Williams, Ann, Marsh, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916317/
https://ncbi.nlm.nih.gov/pubmed/24516549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087329
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