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Distinct DNA Binding Sites Contribute to the TCF Transcriptional Switch in C. elegans and Drosophila

Regulation of gene expression by signaling pathways often occurs through a transcriptional switch, where the transcription factor responsible for signal-dependent gene activation represses the same targets in the absence of signaling. T-cell factors (TCFs) are transcription factors in the Wnt/ß-cate...

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Autori principali: Bhambhani, Chandan, Ravindranath, Aditi J., Mentink, Remco A., Chang, Mikyung V., Betist, Marco C., Yang, Yaxuan X., Koushika, Sandhya P., Korswagen, Hendrik C., Cadigan, Ken M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916239/
https://ncbi.nlm.nih.gov/pubmed/24516405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004133
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