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T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes

The 20S proteasome is almost exclusively localized within cells. High levels of extracellular proteasomes are also found circulating in the blood plasma of patients suffering from a variety of inflammatory, autoimmune and neoplastic diseases. However, the origin of these proteasomes remained enigmat...

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Detalles Bibliográficos
Main Authors: Bochmann, Isabel, Ebstein, Frédéric, Lehmann, Andrea, Wohlschlaeger, Jeremias, Sixt, Stephan Urs, Kloetzel, Peter-Michael, Dahlmann, Burkhardt
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916118/
https://ncbi.nlm.nih.gov/pubmed/24304442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12160
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