Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.

Previous studies had revealed that DNA with partial similarity to the myc oncogene (N-myc) is frequently amplified in human neuroblastoma cell lines and neuroblastoma tumors. We show here for one patient that N-myc amplification is confined to the neuroblastoma tumor and is not present in normal tis...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schwab, M, Ellison, J, Busch, M, Rosenau, W, Varmus, H E, Bishop, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6589638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.15.4940
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