Therapeutic Evaluation of Epstein-Barr Virus-encoded Latent Membrane Protein-1 Targeted DNAzyme for Treating of Nasopharyngeal Carcinomas

The ability of the 10–23 DNAzyme to specifically cleave RNA with high efficiency has fuelled expectation that this agent may have useful applications for targeted therapy. Here, we, for the first time, investigated the antitumor and radiosensitizing effects of a DNAzyme (DZ1) targeted to the Epstein...

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Hlavní autoři: Cao, Ya, Yang, Lifang, Jiang, Wuzhong, Wang, Xiaoyi, Liao, Weihua, Tan, Guolin, Liao, Yuping, Qiu, Yuanzheng, Feng, Deyun, Tang, Faqing, Hou, Bob L, Zhang, Ling, Fu, Jia, He, Fengjiao, Liu, Xiaoyu, Jiang, Wenjuan, Yang, Tubao, Sun, Lun-Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916047/
https://ncbi.nlm.nih.gov/pubmed/24322331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.257
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