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Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases

Microdeletion of the human CHRNA7 gene (α7 nicotinic acetylcholine receptor, nAChR) as well as dysfunction in N-methyl-D-aspartate receptors (NMDARs) have been associated with cortical dysfunction in a broad spectrum of neurodevelopmental and neuropsychiatric disorders including schizophrenia. Howev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Hong, Hsu, Fu-Chun, Baumann, Bailey H., Coulter, Douglas A., Lynch, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915878/
https://ncbi.nlm.nih.gov/pubmed/24326163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.11.021
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