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Structure of deoxyhemoglobin Cowtown [His HC3(146) beta----Leu]: origin of the alkaline Bohr effect and electrostatic interactions in hemoglobin.

Hemoglobin Cowtown [His HC3(146)-beta----Leu] exhibits high oxygen affinity and a halved alkaline Bohr effect. X-ray analysis shows the COOH-terminal leucine to be in equilibrium between two positions: one with the salt bridge between the terminal carboxyl and Lys C5(40)alpha intact and the leucyl s...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Perutz, M F, Fermi, G, Shih, T B
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 1984
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6589624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.15.4781
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