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Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy
Adoptive cellular immunotherapy (ACT) is a potentially curative therapy for patients with advanced cancer. Eradication of tumor in mouse models and humans correlates with both a high dose of adoptively transferred cells and cells with a minimally differentiated phenotype that maintain replicative ca...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915736/ https://ncbi.nlm.nih.gov/pubmed/24329803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12135 |
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