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A High-Throughput Technique Reveals the Load- and Site Density-Dependent Kinetics of E-Selectin
The kinetics of bond rupture between receptors and ligand are critically dependent on applied mechanical force. Force spectroscopy of single receptor-ligand pairs to measure kinetics is a laborious and time-consuming process that is generally performed using individual force probes and making one me...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915287/ https://ncbi.nlm.nih.gov/pubmed/24511329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-012-0247-6 |
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