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A High-Throughput Technique Reveals the Load- and Site Density-Dependent Kinetics of E-Selectin

The kinetics of bond rupture between receptors and ligand are critically dependent on applied mechanical force. Force spectroscopy of single receptor-ligand pairs to measure kinetics is a laborious and time-consuming process that is generally performed using individual force probes and making one me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Snook, Jeremy H., Guilford, William H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915287/
https://ncbi.nlm.nih.gov/pubmed/24511329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-012-0247-6
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