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Microvascular sprouting, extension, and creation of new capillary connections with adaptation of the neighboring astrocytes in adult mouse cortex under chronic hypoxia

The present study aimed to determine the spatiotemporal dynamics of microvascular and astrocytic adaptation during hypoxia-induced cerebral angiogenesis. Adult C57BL/6J and Tie2-green fluorescent protein (GFP) mice with vascular endothelial cells expressing GFP were exposed to normobaric hypoxia for...

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Bibliographic Details
Main Authors: Masamoto, Kazuto, Takuwa, Hiroyuki, Seki, Chie, Taniguchi, Junko, Itoh, Yoshiaki, Tomita, Yutaka, Toriumi, Haruki, Unekawa, Miyuki, Kawaguchi, Hiroshi, Ito, Hiroshi, Suzuki, Norihiro, Kanno, Iwao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915210/
https://ncbi.nlm.nih.gov/pubmed/24252848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.201
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