Delayed progesterone treatment reduces brain infarction and improves functional outcomes after ischemic stroke: a time-window study in middle-aged rats

We evaluated the neuroprotective effects of delayed progesterone (PROG) treatment against ischemic stroke-induced neuronal death, inflammation, and functional deficits. We induced transient focal cerebral ischemia in male rats and administered PROG (8 mg/kg) or vehicle intraperitoneally at 3, 6, or...

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Bibliographic Details
Main Authors: Yousuf, Seema, Sayeed, Iqbal, Atif, Fahim, Tang, Huiling, Wang, Jun, Stein, Donald G
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915207/
https://ncbi.nlm.nih.gov/pubmed/24301297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.198
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