Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells

The androgen receptor (AR) stimulates and represses gene expression to promote the initiation and progression of prostate cancer. Here we report that androgen represses the miR-99a/let7c/125b-2 cluster through AR and anti-androgen drugs block the androgen-repression of the miRNA cluster. AR directly...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sun, Dandan, Layer, Ryan, Mueller, Adam C., Cichewicz, Magdalena A., Negishi, Masamitsu, Paschal, Bryce M., Dutta, Anindya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915043/
https://ncbi.nlm.nih.gov/pubmed/23503464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.77
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky