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Molecular Analysis of PIK3CA, BRAF, and RAS Oncogenes in Periampullary and Ampullary Adenomas and Carcinomas

BACKGROUND: Mutations of KRAS are known to occur in periampullary and ampullary adenomas and carcinomas. However, nothing is known about NRAS, HRAS, BRAF, and PIK3CA mutations in these tumors. While oncogenic BRAF contributes to the tumorigenesis of both pancreatic ductal adenocarcinoma and intraduc...

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Bibliographic Details
Main Authors: Schönleben, Frank, Qiu, Wanglong, Allendorf, John D., Chabot, John A., Remotti, Helen E., Su, Gloria H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915027/
https://ncbi.nlm.nih.gov/pubmed/19440799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-009-0917-4
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