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Molecular Analysis of PIK3CA, BRAF, and RAS Oncogenes in Periampullary and Ampullary Adenomas and Carcinomas

BACKGROUND: Mutations of KRAS are known to occur in periampullary and ampullary adenomas and carcinomas. However, nothing is known about NRAS, HRAS, BRAF, and PIK3CA mutations in these tumors. While oncogenic BRAF contributes to the tumorigenesis of both pancreatic ductal adenocarcinoma and intraduc...

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Autors principals: Schönleben, Frank, Qiu, Wanglong, Allendorf, John D., Chabot, John A., Remotti, Helen E., Su, Gloria H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915027/
https://ncbi.nlm.nih.gov/pubmed/19440799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-009-0917-4
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